Long-Term Exposure to Nitrate and Trihalomethanes in Drinking Water and Prostate Cancer: A Multicase–Control Study in Spain (MCC-Spain)

Author:

Donat-Vargas Carolina1234ORCID,Kogevinas Manolis1235,Castaño-Vinyals Gemma1235,Pérez-Gómez Beatriz36,Llorca Javier37,Vanaclocha-Espí Mercedes8,Fernandez-Tardon Guillermo39,Costas Laura310,Aragonés Nuria311,Gómez-Acebo Inés3712,Moreno Victor3131415,Pollan Marina36,Villanueva Cristina M.1235

Affiliation:

1. Instituto de Salud Global de Barcelona (ISGlobal), Barcelona, Spain

2. Universitat Pompeu Fabra (UPF), Barcelona, Spain

3. CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

4. Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

5. Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain

6. Cancer and Environmental Epidemiology Unit, National Centre for Epidemiology, Carlos III Institute of Health, Madrid, Spain

7. Faculty of Medicine, University of Cantabria, Spain

8. Cancer and Public Health Area, Foundation for the Promotion of Health and Biomedical Research-Public Health Research (FISABIO), Valencia, Spain

9. Health Research Institute of Asturias (ISPA), Oviedo, Spain

10. Cancer Epidemiology Research Programme, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain

11. Epidemiology Section, Public Health Division, Department of Health of Madrid, Madrid, Spain

12. Instituto de Investigación Sanitaria Valdecilla (IDIVAL), Santander, Spain

13. Unit of Biomarkers and Susceptibility, Cancer Prevention and Control Program, Catalan Institute of Oncology (ICO), Hospitalet de Llobregat, Spain

14. Colorectal Cancer Group, IDIBELL, Hospitalet de Llobregat, Spain

15. Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference71 articles.

1. Epidemiology of Prostate Cancer

2. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

3. Cancer incidence in Spain, 2015

4. IARC (International Agency for Research on Cancer). 2018. Global Cancer Observatory: Cancer Today. Ferlay J, Ervik M, Lam F, Colombet M, Mery L, Piñeros M, et al., eds. Lyon, France: IARC.

5. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

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