1. MUllerian ducts (17). Decrease in FSH maternal estrogens. Increase in the basal
2. secretion from fetal pituitary-due to ele- levels of estrogens at this very early period
3. vated maternal estrogen levels-may have of development may therefore have a
4. an inverse effect on Sertoli-cell prolifera- deleterious effect on development of male
5. tion and secretion of MIS. It has also been reproductive organs. Furthermore endoge