Rebuttal and Critical Review of Andersen et al.'s D4 PBPK Model

Author:

Luu H-M D

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference45 articles.

1. Bioavailability of octamethylcyclotetrasiloxane (D(4)) after exposure to silicones by inhalation and implantation.

2. Kirkpatrick D. 14 C-D 4 Pharmacokinetics in the Rat Following Intravenous Administration. Huntingdon Research Center Ltd. Sponsored by the Silicone Environment Health and Safety Council. Midland MI:Dow Corning Corporation 1995.

3. Disposition of radioactivity in Fischer 344 rats after single and multiple inhalation exposure to14C-octamethylcyclotetrasiloxane - D4;Plotzke K;Drug Metab Dispos,2000

4. Jovanovic M. Disposition of Polydimethylsiloxane 10 cst in Fischer 344 rats Following a Single Exposure by Oral Gavage. Dow Corning Internal Report 2000-I0000-49106. Midland MI:Dow Corning 2000.

5. Meeks RG. Overview of the safety of the components used for the manufacturing of silicone breast implants. Presented at the Safety of Silicone Breat Implants Meeting of the Institute of Medicine 2 July 1998 Washington DC.

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