DNA strand breaks in human nasal respiratory epithelium are induced upon exposure to urban pollution.

Author:

Calderon-Garciduenas L1,Osnaya-Brizuela N1,Ramirez-Martinez L1,Villarreal-Calderon A1

Affiliation:

1. Experimental Pathology Section, Instituto Nacional de Pediatria, Mexico City, Mexico.

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference37 articles.

1. Cellular adaptation in the origin and development of cancer;Farber E;Cancer Res,1991

2. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways.

3. Hydrogen peroxide induces DNA single strand breaks in respiratory epithelial cells

4. Lee JG Madden MC Reed W Adler KB Devlin RB. Use of the single cell gel electrophoresis assay (SCGE) for detection of oxidant-induced DNA single strand breaks (ssb) in human Iung cells. Presented at the American Thoracic Society Conference 22-25 May 1994 Boston MA.

5. Hanley NM Kozumbo WJ Costa DL Tice RR Madden MC. Induction of DNA single strand breaks in Iung cells by ozone exposure in vivo and in vitro. Am Rev Respir Dis 147:A 670 (1993).

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