PBPK modeling/Monte Carlo simulation of methylene chloride kinetic changes in mice in relation to age and acute, subchronic, and chronic inhalation exposure.-Reference-Cited by-同舟云学术

PBPK modeling/Monte Carlo simulation of methylene chloride kinetic changes in mice in relation to age and acute, subchronic, and chronic inhalation exposure.

Published:1996-08 Issue:8 Volume:104 Page:858-865
ISSN:0091-6765
Container-title:Environmental Health Perspectives
language:en
Short-container-title:Environmental Health Perspectives

Author:

Thomas R S¹,Yang R S¹,Morgan D G¹,Moorman M P¹,Kermani H R¹,Sloane R A¹,O'Connor R W¹,Adkins B¹,Gargas M L¹,Andersen M E¹

Affiliation:

1. Department of Environmental Health, Colorado State University, Fort Collins 80523-1680, USA.

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference30 articles.

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2. Sensitivity of Physiologically Based Pharmacokinetic Models to Variation in Model Parameters: Methylene Chloride

3. Physiologically based pharmacokinetics and the risk assessment process for methylene chloride

4. Age-dependent pharmacokinetic changes of ethylenediamine in Fischer 344 rats parallel to a two-year chronic toxicity study*1

5. Gillette JR Dose species and route extrapolation: general aspects. In: Pharmacokinetics in risk assessment: drinking water and health. Washington DC:National Academy Press 1987;96-158.

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