1. gate was specific for the chemical of inter- The dihydroxy-butane conjugate found
2. est butadiene while the other detected a in human urine is one of two N-acetycys
3. general but important biologic response teine conjugates of butadiene excreted in
4. gene mutation. The analysis for urinary the urine of other mammals exposed to
5. metabolites demonstrated that exposures to high concentrations of butadiene. The pro