1. In the case of DNP isomers activation by virus (HBV) in humans and WHV in
2. liver cytosol contrasts with detoxification by woodchucks results in an enhanced activa
3. microsomal or S-12 fractions (34 35). tion of Trp-P-2 to mutagenic metabolites.
4. Extensive studies now in progress in our This inducing effect has been confirmed
5. laboratory show that the mutagenicity of now by using woodchuck liver cytosolic