Role of metabolic activation in the pathogenesis of chemically induced pulmonary disease: mechanism of action of the lung-toxic furan, 4-ipomeanol.

Author:

Boyd M R

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference37 articles.

1. A Lung Oedema Factor from Mouldy Sweet Potatoes (Ipomoea batatas)

2. Isolation and characterization of 4-ipomeanol, a lung-toxic furanoterpenoid produced by sweet potatoes (Ipomoea batatas)

3. Confirmation by chemical synthesis of the structure of 4-ipomeanol, a lung-toxic metabolite of the sweet potato (Ipomoea batatas);Boyd M. R.;Nature,1972

4. Lung-toxic furanoterpenoids produced by sweet potatoes (Ipomoea batatas) following microbial infection

5. Wilson B. J. and Boyd M. R. Toxins producd by sweet Furarium solanm. In: Mycotoxins I.F.H. Purchase Ed. potato roots infected with Ceratocystis fimbriata and Elsevier Publishing Co. Amsterdam 1974 Chap. 15.

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4. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity;Drug Metabolism and Disposition;2016-07-28

5. Metabolic Activation and Toxicities of Furanoterpenoids;Advances in Molecular Toxicology;2016

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