The use of biochemical and molecular parameters to estimate dose-response relationships at low levels of exposure.

Author:

Andersen M E1,Barton H A1

Affiliation:

1. ICF Kaiser Engineers, Inc., Research Triangle Park, NC 27709, USA. andersenme@aol.com

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference36 articles.

1. U.S. EPA. Proposed guidelines for carcinogen risk assessment. EPA 600-P-92-003C. Washington:U.S. Environmental Protection Agency Office of Research and Development 1996.

2. Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats;Kociba RJ;Toxicol Appl Pharmacol,1978

3. U.S. NTP. Carcinogenesis Bioassay of 2 3 7 8-Tetrachlorodibenzo-p-dioxin (CAS No. 1746-01-6) in Osborne-Mendel Rats and B6C3F1 Mice (Gavage Study). Tech Rpt No 209. Research Triangle Park NC:U.S. National Toxicology Program 1982.

4. Abbott BD Birnbaum LS Pratt RM. 2 3 7 8-TCDD-induced hyperplasia of the ureteral epithelium produces hydronephrosis in murine fetuses. Teratology 35:3219-3233(1987).

5. Burelson GR Lebrec H Yang YG Ibanes JD Pennington KN Birnbaum LS. Effect of 2 3 7 8-tetrachlorodibenzo-p-dioxin (TCDD) on influenze virus host resistance in mice. Fundam Appl Toxicol 29:40-47 (1996).

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