RDX Binds to the GABAAReceptor–Convulsant Site and Blocks GABAAReceptor–Mediated Currents in the Amygdala: A Mechanism for RDX-Induced Seizures-Reference-Cited by-同舟云学术

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RDX Binds to the GABAAReceptor–Convulsant Site and Blocks GABAAReceptor–Mediated Currents in the Amygdala: A Mechanism for RDX-Induced Seizures

Published:2011-03 Issue:3 Volume:119 Page:357-363
ISSN:0091-6765
Container-title:Environmental Health Perspectives
language:en
Short-container-title:Environmental Health Perspectives

Author:

Williams Larry R.¹,Aroniadou-Anderjaska Vassiliki²³⁴,Qashu Felicia²,Finne Huckelberry⁴,Pidoplichko Volodymyr²,Bannon Desmond I.¹,Braga Maria F. M.²³⁴

Affiliation:

1. U.S. Army Public Health Command (Provisional), Aberdeen Proving Ground, Maryland, USA

2. Department of Anatomy, Physiology, and Genetics

3. Department of Psychiatry and

4. Neuroscience Program, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference49 articles.

1. Soman induces ictogenesis in the amygdala and interictal activity in the hippocampus that are blocked by a GluR5 kainate receptor antagonist in vitro

2. Primary brain targets of nerve agents: The role of the amygdala in comparison to the hippocampus

3. Pathology and pathophysiology of the amygdala in epileptogenesis and epilepsy

4. Input-specific LTP and depotentiation in the basolateral amygdala

5. Mechanisms regulating GABAergic inhibitory transmission in the basolateral amygdala: implications for epilepsy and anxiety disorders

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2. Gene Expression and Pathway Analysis in Rat Brain and Liver After Exposure to Royal Demolition Explosive (Hexahydro-1,3,5-Trinitro-1,3,5-Triazine);International Journal of Toxicology;2023-03-20

3. Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2;Archives of Toxicology;2023-03-13

4. Building a Network of Adverse Outcome Pathways (AOPs) Incorporating the Tau-Driven AOP Toward Memory Loss (AOP429);Journal of Alzheimer's Disease Reports;2022-06-07

5. The seizure‐inducing plastic explosive RDX inhibits the α 1 β 2 γ 2 GABA _A receptor;Annals of Clinical and Translational Neurology;2022-03-24

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