A 2-year dose-response study of lesion sequences during hepatocellular carcinogenesis in the male B6C3F(1) mouse given the drinking water chemical dichloroacetic acid.
Author:
Affiliation:
1. Wood Hudson Cancer Research Laboratory, Newport, Kentucky 41071-4701, USA. jcarter@woodhudson.org
Publisher
Environmental Health Perspectives
Subject
Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health
Reference54 articles.
1. Preneoplastic lesions as end points in carcinogenicity testing I. Hepatic preneoplasia
2. Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate
3. Carter HW Carter JH Richmond RE DeAngelo AB Nesnow S. 2001a. Dichloroacetic acid alters cell proliferation and cell death (apoptosis) in premalignant hepatic lesions in B6C3F 1 male mice. In: Safety of Water Disinfection: Balancing Chemical and Microbial Risks (GF Craun ed). Washington DC:ILSI Press 559-566.
4. Biochemical, pathologic and morphometric alterations induced in male B6C3F1 mouse liver by short-term exposure to dichloroacetic acid
5. Carter JH Carter HW DeAngelo AB. 1995b. Chronic toxicity of dichloroacetic acid (DCA) in the male B6C3F 1 mouse. In: Fifth Workshop on Mouse Liver Tumors Summary Report. Washington DC:International Life Sciences Institute 63.
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