Role of genotoxic and nongenotoxic effects in multistage carcinogenicity of aromatic amines.

Author:

Neumann H G1,Hammerl R1,Hillesheim W1,Wildschütte M1

Affiliation:

1. Institute of Pharmacology and Toxicology, University of Würzburg, Federal Republic of Germany.

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference18 articles.

1. The role of DNA damage in chemical carcinogenesis of aromatic amines

2. The role of partial hepatectomy and of promoters in the formation of tumors in non-target tissues of trans-4-acetylaminostilbene in rats

3. Synergistic effects on the initiation of rat liver tumors by trans-4-acetylaminostilbene and 2-acetylaminofluorene, studied at the level of DNA adduct formation

4. The role of initiating and promoting properties in aromatic amine carcinogenesis. In: Chemical Carcinogenesis, Models and Mechanisms (F. Feo, P. Pani, A. Columbano, and R. Garcea, Eds.), Plenum Press;Neumann H. -G;New York,1988

5. Miller J. A. Lai C. C. Liem A. and Miller E. C. DNA adduct and tumor formation from N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene in the livers of infant male B6C3F1 mice. In: Carcinogenic and Mutagenic Responses to Aromatic Amines and Nitroarenes (C. M. King L. J. Romano and D. Schuetzle Eds.) Elsevier New York 1988 pp. 249-257.

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