Clinical treatment with bisphosphonates and surgical treatment of osteogenesis imperfecta

Abstract

Introduction: Osteogenesis imperfecta is characterized by presenting an alteration in the synthesis of collagen that mainly affects the structure of the bone and its hardness, causing bone fragility and abundant deformations. Generally, the main cause of hospital admission is long bone fractures, which must be treated very diligently to avoid permanent sequelae, with rapid consolidation of these fractures being a pathognomonic characteristic. Being a genetic disease, a definitive treatment is unknown, therefore, conventional treatment is symptomatic and a specific procedure will be carried out for each case, which will help maintain an acceptable lifestyle for these patients. General objective: Describe the conventional treatment in patients diagnosed with osteogenesis imperfecta.Methodology: Bibliographic review type study, where the information will be collected from scientific search engines Scopus, Taylor and Francis, Web of Science, PubMed, Elsevier, and Redalyc; The following keywords and with the Boolean operators OR, AND and NOT.Conclusions: Since its first description, there have been improvements in the classification, and in terms of specific symptomatic treatment they have visibly improved, however, there is no curative basic treatment to date.