Chemoprevention of 2-amino-1-methyl-6-phenyli-midazo [4, 5-b] pyridine-induced carcinogen-DNA adducts by Chinese cabbage in rats

Author:

Tan Wen

Publisher

Baishideng Publishing Group Inc.

Subject

Gastroenterology,General Medicine

Reference14 articles.

1. Ji BT, Devesa SS, Chow WH, Jin F, Gao YT. Colorectal cancer incidence trends by subsite in urban Shanghai, 1972-1994. Cancer Epidemiol Biomarkers Prev 1998;7:661-666.

2. A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

3. Boobis AR, Lynch AM, Murray S, de la Torre R, Solans A, Farré M, Segura J, Gooderham NJ, Davies DS. CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans. Cancer Res 1994;54:89-94.

4. Identification of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA

5. Analysis of DNA Adducts of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Rat and Human Tissues by Alkaline Hydrolysis and Gas Chromatography/Electron Capture Mass Spectrometry: Validation by Comparison with 32P-Postlabeling

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