CQ5 Which treatment is more effective for long term management of children with asthma, leukotriene receptor antagonist or inhaled corticosteroid?

Author:

Miura Taro1,Hiraguchi Yukiko2,Sugiyama Takeshi3,Arakawa Hirokazu4

Affiliation:

1. Department of Pediatrics, Tokyo Medical University

2. Department of Pediatrics, Center of Allergy and Clinical Immunology, Osaka Saiseikai Nakatsu Hospital

3. Department of Pediatrics, University of Yamanashi School of Medicine

4. Department of Pediatrics, Gunma University Graduate School of Medicine

Publisher

Japanese Society of Pediatric Allergy and Clinical Immunology

Subject

Ocean Engineering

Reference22 articles.

1. 1) Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. NIH Publication ; National Heart, Lung and Blood Institute ; Bethesda, MD : 2002. http://www.ginasthma.org/pdf/GINA.Report.2010.pdf

2. 3) Chauhan BF, Ducharme FM. Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. Cochrane Database Syst Rev. 2012 May 16 ; CD002314.

3. 4) Caffey LF, et al. A crossover comparison of fluticasone propionate and montelukast on inflammatory indices in children with asthma. Pediatr Asthma Allergy Immunol 2005 ; 18 : 123-130.

4. 5) FPD40013 (unpublished data only). FPD40013 A randomized, double-blind, double dummy, parallel group comparison of fluticasone propionate inhalation powder (50 mcg BID) via discus with oral montelukast (5 mg QD) chewable tablets in children 6-12 years of age with persistent asthma. GlaxoSmithKline Clinical Trial Register 2005.

5. 6) Garcia-Garcia ML, et al. Montelukast, compared with fluticasone, for control of asthma among 6- to 14-year-old patients with mild asthma : the MOSAIC study. Pediatrics 2005 ; 116 : 360-369.

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1. Japanese guidelines for childhood asthma 2020;Allergology International;2020-07

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