Analysis of the infectional profile of diabetic patients infected by COVID 19 in the period of 2020 – 2021 Análise do perfil de infecção dos pacientes diabéticos infectados pela COVID 19 no período de 2020-2021

Abstract

The COVID-19 disease has as its etiological agent the SARS-CoV-2, a RNA virus that causes severe respiratory syndrome. Diabetes mellitus is one of the significant risk factors for COVID-19 due to the weakened immune response of these patients and widely distribution of ACE2 in diferent organs. ACE2 is a receptor that antagonizes the RAS system, and is  related to the clinical symptoms of COVID 19 .Its expression in the islet cells and exocrine pancreas suggest the susceptibility for SARS-CoV 2 infection in diabetic patients. This stydy analyses the infeccional profile of diabetic patients infeccted by COVID-19 in the city of Maceió. A research was performed in the year of 2020-2021 in english idiom in the database PubMed using the descriptors “ACE receptor” AND “Covid”, “Covid” AND “Diabetes” AND “ ACE receptor” .The criteria of inclusion and exclusion established was the relevance and approach based on the theme to be discussed.It was collected data about confirmed deaths by Covid 19 according to preexisting comorbidities in the city of Maceió – AL shown in the graphics , expressing an average mortality among patients infected by Covid and preexisting Diabetes Mellitus. This study shows a reduction in the percentage of mortality in diabetic patients infected by Covid-19 seen in view of the adoption of measures to restrict the spread of the virus, reducing the numbers of infecion, especially the risk group, in addition to the vaccination campaign which culminated in positive results to the reduction in the mortality in infected diabetics.