FXR activation by obeticholic acid or nonsteroidal agonists induces a human-like lipoprotein cholesterol change in mice with humanized chimeric liver-Reference-Cited by-同舟云学术

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FXR activation by obeticholic acid or nonsteroidal agonists induces a human-like lipoprotein cholesterol change in mice with humanized chimeric liver

Published:2018 Issue:6 Volume:59 Page:982-993
ISSN:0022-2275
Container-title:Journal of Lipid Research
language:en
Short-container-title:Journal of Lipid Research

Author:

Papazyan Romeo,Liu Xueqing,Liu Jingwen,Dong Bin,Plummer Emily M.,Lewis Ronald D.,Roth Jonathan D.,Young Mark A.

Funder

Intercept Pharmaceuticals, Inc.

Publisher

Elsevier BV

Subject

Cell Biology,Endocrinology,Biochemistry

Reference70 articles.

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3. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis;Sinal;Cell.,2000

4. The farnesoid X-receptor is an essential regulator of cholesterol homeostasis;Lambert;J. Biol. Chem.,2003

5. Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice;Hanniman;J. Lipid Res.,2005

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