Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody-Reference-Cited by-同舟云学术

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Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody

Published:2015-11 Issue:11 Volume:56 Page:2124-2132
ISSN:0022-2275
Container-title:Journal of Lipid Research
language:en
Short-container-title:Journal of Lipid Research

Author:

Schroeder Krista M.,Beyer Thomas P.,Hansen Ryan J.,Han Bomie,Pickard Richard T.,Wroblewski Victor J.,Kowala Mark C.,Eacho Patrick I.

Publisher

Elsevier BV

Subject

Cell Biology,Endocrinology,Biochemistry

Reference38 articles.

1. PCSK9: a convertase that coordinates LDL catabolism;Horton;J. Lipid Res.,2009

2. PCSK9 function and physiology;Peterson;J. Lipid Res.,2008

3. Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells;McNutt;J. Biol. Chem.,2007

4. Adenoviral-mediated expression of PCSK9 in mice results in a low- density lipoprotein receptor knockout phenotype;Maxwell;Proc. Natl. Acad. Sci. USA.,2004

5. Decreased plasma cholesterol and hypersensitivity to statins in mice lacking PCSK9;Rashid;Proc. Natl. Acad. Sci. USA.,2005

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1. New Biological Therapies for Low-Density Lipoprotein Cholesterol;Canadian Journal of Cardiology;2023-12

2. PCSK9 inhibitors: current status and emerging frontiers in lipid control;Expert Review of Cardiovascular Therapy;2023-11-23

3. PCSK9 Inhibition in Atherosclerotic Cardiovascular Disease;Current Pharmaceutical Design;2023-09-06

4. Targeting PCSK9 to tackle cardiovascular disease;Pharmacology & Therapeutics;2023-09

5. Construction and application of a human scFv phage display library based on Cre‑LoxP recombination for anti‑PCSK9 antibody selection;International Journal of Molecular Medicine;2020-12-16

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