Fifty years of lyase and a moment of truth: sphingosine phosphate lyase from discovery to disease
Author:
Funder
National Institutes of Health
Ultragenyx Pharmaceutical
Swim Across America Foundation
Publisher
Elsevier BV
Subject
Cell Biology,Endocrinology,Biochemistry
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3. Studies on the biosynthesis and degradation of sphingosine bases;Stoffel;Chem. Phys. Lipids.,1970
4. Sphingosine-1-phosphate lyase (SPL) is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5′-phosphate binding domain exposed to the cytosol;Ikeda;Biochem. Biophys. Res. Commun.,2004
5. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism;Bourquin;Structure.,2010
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