Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Endocrinology,Biochemistry
Reference41 articles.
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2. Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis;Davis;J. Biol. Chem.,2004
3. Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia;Davies;J. Biol. Chem.,2005
4. In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461;Van Heek;J. Pharmacol. Exp. Ther.,1997
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