Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway-Reference-Cited by-同舟云学术

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Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway

Published:2017-01 Issue:1 Volume:58 Page:60-71
ISSN:0022-2275
Container-title:Journal of Lipid Research
language:en
Short-container-title:Journal of Lipid Research

Author:

Alecu Irina,Othman Alaa,Penno Anke,Saied Essa M.,Arenz Christoph,von Eckardstein Arnold,Hornemann Thorsten

Funder

European Commission Seventh Framework Programme

Swiss National Science Foundation

Novartis Foundation

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Cell Biology,Endocrinology,Biochemistry

Reference54 articles.

1. Human and murine serine-palmitoyl-CoA transferase–cloning, expression and characterization of the key enzyme in sphingolipid synthesis;Weiss;Eur. J. Biochem.,1997

2. A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis;Hanada;J. Biol. Chem.,1997

3. Cloning and characterization of Lcb1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids;Buede;J. Bacteriol.,1991

4. Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids;Penno;J. Biol. Chem.,2010

5. Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals;Zitomer;J. Biol. Chem.,2009

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