Author:
Vaira L A,Hopkins C,Sandison A,Manca A,Machouchas N,Turilli D,Lechien J R,Barillari M R,Salzano G,Cossu A,Saussez S,De Riu G
Abstract
AbstractBackgroundOlfactory dysfunction represents one of the most frequent symptoms of coronavirus disease 2019, affecting about 70 per cent of patients. However, the pathogenesis of the olfactory dysfunction in coronavirus disease 2019 has not yet been elucidated.Case reportThis report presents the radiological and histopathological findings of a patient who presented with anosmia persisting for more than three months after infection with severe acute respiratory syndrome coronavirus-2.ConclusionThe biopsy demonstrated significant disruption of the olfactory epithelium. This shifts the focus away from invasion of the olfactory bulb and encourages further studies of treatments targeted at the surface epithelium.
Publisher
Cambridge University Press (CUP)
Subject
Otorhinolaryngology,General Medicine
Cited by
75 articles.
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