Nasal tuberculosis – an update of current clinical and laboratory investigation

Abstract

AbstractObjective:To report a case of primary nasal tuberculosis, and to discuss the diagnostic difficulties encountered.Setting:A teaching hospital in Norwich, UK.Method:Case report and review of the English language literature concerning tuberculosis affecting the head and neck region.Result:The diagnosis of nasal tuberculosis is based on: histological identification of granulomatous inflammation; positive testing for acid-alcohol resistant bacilli; and positive culture. Newer diagnostic tests have the advantage of speed and improved accuracy, but are not as yet completely evaluated for the diagnosis of extra-pulmonary tuberculosis.Conclusion:It is important to consider nasal tuberculosis in the initial differential diagnosis. The quest to exclude a malignancy may lead to unacceptable delays in treatment.