Delayed brainstem auditory evoked reponses in experimental diabetes mellitus

Author:

Buller N.,Laurian N.,shvili I.,Laurian L.

Abstract

AbstractThe brainstem auditory evoked responses (BAER) were utilized for the evaluation of central neural transmission in alloxan-induced diabetes in rats. The mean latencies of waves I, III, V and the interpeak latencies III-V and I-V were prolonged in diabetic rats as compared to the same rats before alloxan administration. The incidence of abnormal BAER was more frequent in the group of rats with severe diabetes (82 per cent) than in mildly diabetic animals (42 per cent). Our results may suggest the presence of a central neuropathy in experimental diabetes, which can be detected by the method of BAER.

Publisher

Cambridge University Press (CUP)

Subject

Otorhinolaryngology,General Medicine

Reference18 articles.

1. Drugs producing diabetes through damage of the insulin secreting cells;Rerup;Pharmacologic Reviews,1970

2. Nerve Conduction Changes in Experimental Diabetes*

3. Diabetic control and peripheral neuropathy;Windebank;Mayo Clinic Proceedings,1963

4. Pancreatic Islet-Cell Toxicity

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