Sudden sensorineural deafness and hormone replacement therapy

Author:

Strachan David

Abstract

AbstractWhilst the oral contraceptive pill (OC) has been implicated on a number oif occasions as a cause of sensorineural hearing loss, there are no published reports linking hormone replacement therapy (HRT) to otological symptoms. A case of sensorineural loss with tinnitus following commencement of HRT is described, followed by a discussion outlining the fundamental differences between the OC and HRT, thus expaining why a vascular aetiology is unlikely. It is hypothesized that otological symptoms in such cases may be due to the effect of oestrogens on electrolyte balance disturbing inner ear function and also a direct effect on the auditory pathways mediated in part by alterations in neurotransmitter receptor concentrations.

Publisher

Cambridge University Press (CUP)

Subject

Otorhinolaryngology,General Medicine

Reference17 articles.

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3. Acute deafness associated with Depoprogesterone

4. The long-term effect of oral and percutaneous estradiol on plasma renin substrate and blood pressure.

5. Fluctuating sensorineural hearing impairment associated with the menstrual cycle;Miller;Journal of Audiological Research,1967

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