Author:
Bath Andrew P.,Walsh Rory M.,Bance Manohar L.
Abstract
AbstractWe report the first case in the world literature of deliberate ablation of vestibular function in unilateral Meniere's disease with aminoglycoside eardrops (Garasone).These findings give conclusive proof that Garasone eardrops, and by implication, all topical aminoglycoside ear drops can be vestibulotoxic in the presence of a tympanic membrane defect. The lower concentration of gentamicin in Garasone, in comparison to the standard intratympanic preparations for chemical ablation of vestibular function, may also offer a reduction in the potential risk of cochleotoxocity.
Publisher
Cambridge University Press (CUP)
Subject
Otorhinolaryngology,General Medicine
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