Abstract
AbstractBackgroundThis paper reports a case series of three elderly patients who were regularly attending ENT clinic every four to six weeks for ear canal care to address chronic otitis externa. All three patients had been taking bisphosphonate alendronic acid for years, and it is suspected that this drug was partly to blame for the progression of their chronic ear conditions.ResultsSome improvements were noted when the bisphosphonate was discontinued. The regular microsuctioning, and application of topical antibiotics with steroids, provided temporary relief of symptoms. The present pandemic shut down the routine clinic and the patients were not seen for four to five months. On latest review, it was a surprise to see that their ears seemed to have significantly improved, with healthy re-epithelialisation.ConclusionIt is thus believed that excessive and repeated microsuctioning in bisphosphonate-induced osteonecrosis of that external ear canal can delay re-epithelialisation, and gradually prolonging the intervals between microsuctioning could help in overall resolution of the disease.
Publisher
Cambridge University Press (CUP)
Subject
Otorhinolaryngology,General Medicine
Reference10 articles.
1. Bisphosphonate-induced osteonecrosis of the ear canal: our experience and a review of the literature
2. 2 Side effects for all bisphosphonates. In: https://bnf.nice.org.uk/drug/alendronic-acid.html#sideEffects [27 September 2020]
3. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic
4. Bisphosphonates for osteoporosis – where do we go from here?;Whitaker;N Engl J Med,2012
5. 6 International Classification of Diseases 11th Revision. In: https://www.who.int/classifications/icd/en/ [17 October 2020]
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