Individual variation and effect of priming dose level on establishment, growth and fecundity ofCooperia oncophorain re-infected calves
-
Published:2004-01
Issue:1
Volume:128
Page:99-109
-
ISSN:0031-1820
-
Container-title:Parasitology
-
language:en
-
Short-container-title:Parasitology
Author:
KANOBANA K.,PLOEGER H. W.,EYSKER M.,VERVELDE L.
Abstract
We investigated the effect of bovine anamnestic immunity on a range of parasitological variables. To this end, calves were primed with a single oral dose of 30 000 or 100 000 infective larvae (L3) ofCooperia oncophora, drenched with anthelmintic, maintained worm free in the following 2·5 months and subsequently re-infected with 100 000 L3. Parasitological profiles of low, intermediate, and high responders were compared. The reduction in establishment of the worms was shown by a lower worm burden and increased percentage of fourth-stage (L4) larvae. Worm length and fecundity were similarly reduced by both priming doses but, the speed by which the effect occurred differed between animals primed with 30 000 or 100 000 L3. The difference in establishment between the responder types demonstrates that the ability of intermediate responders to mount a more effective and faster immune response compared to low responders is sustained after secondary infection.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Animal Science and Zoology,Parasitology
Reference31 articles.
1. VAN DIEMEN, P. M. , PLOEGER, H. W. , NIEUWLAND, M. G. , RIETVELD, F. W. & PARMENTIER, H. K. (1997).Recognition of low molecular weight Cooperia oncophora antigens after primary and trickle infection of calves with third-stage infective larvae.International Journal for Parasitology 26, 1305–1310. 2. Mechanisms underlying resistance to nematode infection 3. STEAR, M. J. , BAIRDEN, K. , DUNCAN, J. L. , HOLMES, P. H. , McKELLAR, Q. A. , PARK, M. , STRAIN, S. , MURRAY, M. , BISHOP, S. C. & GETTINBY, G. (1997 b).How hosts control worms.Nature, London 389, 27. 4. STEAR, M. J. , BAIRDEN, K. , BISHOP, S. C. , BUITKAMP, J. , DUNCAN, J. L. , GETTINBY, G. , McKELLAR, Q. A. , PARK, M. , PARKINS, J. J. , REID, S. W. , STRAIN, S. & MURRAY, M. (1997 a).The genetic basis of resistance to Ostertagia circumcincta in lambs.Veterinary Journal 154, 111–119. 5. SEATON, D. S. , JACKSON, F. , SMITH, W. D. & ANGUS, K. W. (1989).Development of immunity to incoming radiolabelled larvae in lambs continuously infected with Ostertagia circumcincta .Research in Veterinary Science 46, 241–246.
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|