Author:
SIDDIQUI RUQAIYYAH,DUDLEY RICKY,KHAN NAVEED AHMED
Abstract
SUMMARYThe ability of cyst-forming protists such asAcanthamoebato escape death by transforming into a cyst form, that is resistant to harsh physiological, environmental and pharmacological conditions, has continued to pose a serious challenge to human and animal health. A complete understanding of the fundamental principles of genome evolution and biochemical pathways of cellular differentiation offers unprecedented opportunities to counter detrimental outcomes.Acanthamoebacan elude inhospitable conditions by forming cysts. Here we unravel the processes involved in the phenotypic switching ofAcanthamoeba, which are critical in our efforts to find potential targets for chemotherapy.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Animal Science and Zoology,Parasitology
Cited by
12 articles.
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