Abstract
AbstractAngiostrongylus cantonensis (rat lungworm) is a tropical and subtropical parasitic nematode, with infections in humans causing angiostrongyliasis (rat lungworm disease), characterized by eosinophilic meningitis. Hawaii has been identified as a global hotspot of infection, with recent reports of high infection rates in humans, as well as rat definitive and snail intermediate hosts. This study investigated variation in A. cantonensis infection, both prevalence and intensity, in wild populations of two species of rats (Rattus exulans and R. rattus) and one species of snail (Parmarion martensi). An overall infection prevalence of 86.2% was observed in P. martensi and 63.8% in rats, with R. exulans (77.4%) greater than R. rattus (47.6%). We found infections to vary with environmental and host-related factors. Body mass was a strong predictor of infection in all three species, with different patterns seen between sexes and species of rats. Infection prevalence and intensity for R. exulans were high in May 2018 and again in February 2019, but generally lower and more variable during the intervening months. Information on sources of variability of infection in wild host populations will be a crucial component in predicting the effectiveness of future disease surveillance or targeted management strategies.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Animal Science and Zoology,Parasitology
Reference42 articles.
1. The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
2. Species of Angiostrongylus (Nematoda: Metastrongyloidea) in wildlife: a review;Spratt;International Journal for Parasitology: Parasites and Wildlife,2015
3. Age- and sex-related differences in diet selection byRattus rattuson Stewart Island, New Zealand
4. Changing epidemiology of Angiostrongyliasis cantonensis in Okinawa Prefecture, Japan;Asato;Japanese Journal of Infectious Diseases,2004
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献