Author:
COUVREUR B.,JACQUET D.,BOLLEN A.,LE RAY D.
Abstract
Leishmania infantum immunoelectrophoretic antigen 24 (AG
24), a
visceral leishmaniasis associated immunodominant
antigen, has been characterized with a monospecific antiserum by combining
SDS–PAGE, immunoblotting, metabolic
labelling, radio-immunoprecipitation and in vitro poly A+
mRNA translation. AG 24 appeared to correspond to a multi-antigen family
of
6–9 members ranging from 20 to 31 kDa and proteinic by nature with
no post-translational modifications.
A similar banding pattern was recognized by infection sera. AG 24 was
not found exposed on the cell surface.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Animal Science and Zoology,Parasitology
Cited by
4 articles.
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