Author:
André Charles,Jaber-Filho Jorge A.,Bento Rafael M.A.,Damasceno Lúcia M.P.,Aquino-Neto Francisco R.
Abstract
ABSTRACTObjective: To describe a case of marijuanainduced delirium and the techniques used to detect psychoactive agents and metabolites in urine.Methods: A case of delirium following involuntary ingestion of cannabis is described. A urine sample was analyzed applying various chemical procedures, using high-resolution gas chromatography coupled with mass spectrometry technique. 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid was quantified by the methodology for steroids and cannabis.Results: A 26-year-old man was hospitalized with severe agitation and psychotic behavior 36 hours after suspected involuntary ingestion of cannabis contained in a brigadeiro, a typical Brazilian cookie, consumed during a party. Treatment with neuroleptics resulted in complete regression of the symptoms over 2 weeks. The urine sample revealed marijuana ingestion, demonstrated by the presence of its metabolite, 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid inConclusion: Severe delirium can follow oral ingestion of cannabis integrated into homemade cookies.
Publisher
Cambridge University Press (CUP)
Subject
Psychiatry and Mental health,Neurology (clinical)
Cited by
16 articles.
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