The Role of Complex Combination Therapy in the Treatment of Refractory Bipolar Illness

Author:

Post Robert M.,Frye Mark A.,Leverich Gabriele S.,Denicoff Kirk D.

Abstract

AbstractIn this article, we present rationales for using complex combination therapy in treatment-refractory bipolar patients and discuss the agents available for use in this therapeutic approach. We review a case example of successful remission that was achievable only with complex combination therapy, and examine its theoretical implications. Practical approaches to devising the optimal complex combination treatment for individual patients are explained, and we look to the development of new methodologies and a more systematic database for decision making in the future.

Publisher

Cambridge University Press (CUP)

Subject

Psychiatry and Mental health,Neurology (clinical)

Cited by 14 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Psychopharmacological Recovery-Oriented Treatments in Bipolar Disorders;Recovery and Major Mental Disorders;2022

2. A History of the Pharmacological Treatment of Bipolar Disorder;International Journal of Molecular Sciences;2018-07-23

3. Unique design issues in clinical trials of patients with bipolar affective disorder;Journal of Psychiatric Research;2003-01

4. Quetiapine in the treatment of rapid cycling bipolar disorder;Bipolar Disorders;2002-09-25

5. The Stanley Foundation Bipolar Network;British Journal of Psychiatry;2001-06

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