Assessing the zoonotic potential ofAscaris suumandTrichuris suis: looking to the future from an analysis of the past

Abstract

AbstractThe two geohelminths,Ascaris lumbricoidesandTrichuris trichiura, infect more than a billion people worldwide but are only reported sporadically in the developed part of the world. In contrast, the closely related speciesA. suumandT. suisin pigs have a truly global distribution, with infected pigs found in most production systems. In areas where pigs and humans live in close proximity or where pig manure is used as fertilizer on vegetables for human consumption, there is a potential risk of cross-infections. We therefore review this relationship betweenAscarisandTrichurisin the human and pig host, with special focus on recent evidence concerning the zoonotic potential of these parasites, and identify some open questions for future research.