Abstract
AbstractThree cows were treated with different levels of compound “E” which is known to have strong filaricidal activity. In all three animals the number of microfilariae ofOnchocerca gutturosadeclined after treatment. At autopsy most of the adult worms found were dead and in those still living embryogenesis appeared to have ceased.It is concluded that, despite the disadvantages, this system represents a possible way of assessing onchocercicidal activity before undertaking human trials.
Publisher
Cambridge University Press (CUP)
Subject
Animal Science and Zoology,General Medicine,Parasitology
Reference7 articles.
1. Studies on Onchocerca gutturosa (Neumann, 1910) and its development in Simulium ornatum (Meigen, 1818). 1. Observations on O. gutturosa in South-East England;Eichler;Journal of Helminthology,1971
2. Studies in rodents and dogs with a new macro- and micro-filaricidal compound;Düwel;Proceedings of the Ninth International Congress on Tropical Medicine and Malaria,1973
3. The effect of Suramin on the immature forms of Onchocera volvulus in the vertebrate host;Duke;Zeitschrift für Tropenmedizin und Parasitologie,1974
4. The effect of levamisole on Onchocerca volvulus
5. Studies onOnchocerca cervicalisRailliet and Henry 1910: I.Onchocerca cervicalisin British Horses
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