Author:
DEW M. A.,BECKER J. T.,SANCHEZ J.,CALDARARO R.,LOPEZ O. L.,WESS J.,DORST S. K.,BANKS G.
Abstract
Background. There is little agreement on whether the
prevalence of psychiatric disorder is elevated in HIV-seropositive
(HIV +) populations compared with uninfected persons. However,
evaluation of this issue has been limited by difficulties of sampling,
study design and failure to control for other risk factors for
disorder.Methods. Prevalence and clinical characteristics of
DSM-III-R major depressive disorder (MDD), generalized anxiety
disorder, adjustment disorder, and alcohol and substance
abuse/dependence were evaluated in a representative sample of HIV +
men attending primary care physicians' offices in a defined
geographical area. Lifetime prevalence at baseline and 1-year rates
during longitudinal follow-up were determined for the 113 HIV + men, as
well as 57 HIV – men, via standardized interview. Multivariate
analyses considered unique and combined effects of HIV serostatus and
other risk factors on likelihood of disorder.Results. Although there were no differences in lifetime
rates prior to baseline, HIV + men were at greater risk for disorders
during the prospective study period. For MDD, this effect was
maintained even after controlling for other risk factors. Several of
these other factors bore their own effects: regardless of HIV
serostatus, men were susceptible to psychopathology if at baseline
they were younger, had a lifetime psychiatric history, or had poor
social supports or a low sense of personal mastery.Conclusions. The risk of certain psychiatric disorders
appears uniquely elevated in HIV + men. Since other factors also
influence risk, interventions designed to minimize psychopathology
during HIV infection should attend to both HIV-related and
non-HIV-related risk factors.
Publisher
Cambridge University Press (CUP)
Subject
Psychiatry and Mental health,Applied Psychology
Cited by
176 articles.
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