In vivo exploration of brain phosphorus 31 metabolism in patients with senile dementia of Alzheimer type

Author:

Mecheri G,Bissuel Y,Dalery J,Terra JL,Balvay G,Roussel B,Marie-Cardine M

Abstract

SummaryIn vivo NMR 31p spectroscopy is a non invasive, non ionizing method of exploration of energy and phospholipid metabolism in the brain. This study consisted of comparing 31p spectra in five patients with Senile Dementia of Alzheimer Type (SDAT) with those of four controls of similar ages. Abnormal phosphonionocsters (PME) concentrations, either high or low, were found in the patients, but statistical analysis did not elicit any significant difference relative to controls.

Publisher

Cambridge University Press (CUP)

Subject

Psychiatry and Mental health

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