Author:
Francis S. M.,Bickerstaffe R.,Clarke J. N.,O'Connell D.,Hurford A. P.
Abstract
SummaryOver 5 years (1987–91), the progeny of rams selected for fast (Low T-half) or slow (High T-half) glucose clearance after an intravenous glucose tolerance test, differed significantly in glucose tolerance. In comparison with an unselected control, the line differences were mainly in the direction of Low T-half. They appear to have arisen during the establishment period, with little evidence of enhanced divergence over the four subsequent years of continued selection (heritability 0·10±0·03). The Low line had higher plasma insulin concentrations during the glucose tolerance test than the High line. Basal plasma concentrations of glucose were lower, and urea higher in the Low than the High line. In addition, carcasses of Low line ram progeny had more subcutaneous fat at the same carcass weight than High line carcasses (11% higher GR in the final year of the experiment). Selection of sheep for glucose clearance appeared to be associated with differential partitioning of nutrients into adipose tissue, the pooled genetic correlation between T-half and GR being −0·28±0·13.
Publisher
Cambridge University Press (CUP)
Subject
Genetics,Agronomy and Crop Science,Animal Science and Zoology
Reference40 articles.
1. Induction of insulin resistance by prolonged suckling or administration of exogenous insulin in lambs;Munro;Proceedings of the Nutrition Society of New Zealand,1985
2. Regulation of nutrient partitioning growth and lactation
3. Role of insulin in food intake, weight gain and lipid deposition in the Zucker obese rat;Stolz;Journal of Nutrition,1982
4. Blair H. T. , Mccutcheon S. N. & Mackenzie D. D. S. (1990). Physiological predictors of genetic merit. In Proceedings of the Eighth Australian Association of Animal Breeding and Genetics, pp. 133–142.
5. Genetic selection of animals differing in obesity using a biochemical parameter;Francis;Journal of Cellular Biochemistry Supplement,1989
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献