A note on the distribution of scrapie in sheep of different ages

Abstract

Natural scrapie can develop in sheep at any age later than about 18 months old. In order to formulate a realistic policy for experimental investigation of the disease as it occurs naturally, it is necessary to understand what factors might affect the incidence in sheep of different ages. Any attempt to use data from commercial sheep flocks to draw conclusions about the age distribution of scrapie cases must make allowance for the fact that the population at risk is being culled on commercial criteria and incurs losses by death from various causes.