The effect of age on halothane susceptibility in pigs

Author:

Carden A. E.,Webb A. J.

Abstract

ABSTRACTThe effect of age on incidence of susceptibility to halothane anaesthesia in pigs was studied on animals that were repeatedly exposed to the anaesthetic. In three trials, 232 Piétrain/Hampshire and 201 Landrace pigs were given three 3-min halothane tests, at 19, 35 and 54 days of age. In a fourth trial 253 Landrace pigs received four 5-min tests, at 21, 35, 49 and 63 days. All pigs were offspring of positive × positive matings. Maximum-likelihood estimates of the probability of positive reactions were 0·47, 0·73 and 0·88 at the three ages in Pietrain/Hampshire; 0·20, 0·63 and 0·60 in the first Landrance trial; and 0·64, 0·86, 0·84 and 0·90 in the second Landrace trial. Thus, in all trials, the incidence of halothane positive reactions increased with age. In both breeds and at all ages, the incidence was lower in males than in females.

Publisher

Cambridge University Press (CUP)

Subject

Animal Science and Zoology

Reference13 articles.

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2. Webb A. J. 1980. The effect of age on the expression of the halothane gene in pigs. 31st A. Mtg Eur. Ass. Anim. Prod., Munich, Paper P5/6.22.

3. Prediction of susceptibility to the porcine stress syndrome

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