The effect of environmental temperature during pregnancy on thermoregulation in the newborn lamb

Abstract

AbstractTwenty-four pregnant Scottish Blackface ewes were divided into three temperature-treatment groups 14 days before expected lambing: closely shorn and kept at 6°C (cold treatment, CD); in full fleece at 26°C (warm treatment, WM); and in full fleece at 6°C (controls, CL). Food allocation and intakes were similar for each group. Their lambs were tested for cold-induced summit metabolic rate capability (SMR) on the day of birth at a mean age of 12 h using water immersion to provide cooling. On the following day, the calorigenic response to subcutaneous injections of noradrenaline (NA) was measured to assess non-shivering thermogenesis capability. The ewes were blood-sampled during pregnancy and the lambs before and after the SMR test.In the ewes, blood glucose and free fatty acid levels were higher during cold treatment, but not significantly so. Blood glucose was lower in lambs from CD ewes (CD lambs) before SMR tests; other differences were not significant.During the cold test, SMR was highest in CD lambs, but not significantly so. Rectal temperature declined least during test in the CD lambs (P < 0·05).The peak metabolic response (PMR) following NA injection was about 1·5 times greater in CD lambs than in the CL and WM lambs (P < 0·05). The mean elevation of PMR over thermoneutral metabolic rate was respectively: 2·8, 1·8 and 1·7 times in the CD, CL and WM lambs (P < 0·05), and this elevation was sustained for longer in the CD lambs (P < 0·01). Thus, the total metabolic response to NA was markedly greater in CD lambs.It was concluded that cold exposure during late pregnancy favoured the deposition of (or checked the normal decline in) foetal brown adipose tissue, so raising the neonatal capacity for non-shivering thermogenesis.