The neurobiological basis of autism from a developmental perspective

Author:

AKSHOOMOFF NATACHA,PIERCE KAREN,COURCHESNE ERIC

Abstract

Autism is a neurobiological disorder that is diagnosed through careful behavioral assessment in early childhood. In this paper, we review recent studies that have attempted to reveal the underlying causes of autism using a variety of techniques. Particular emphasis is placed on techniques that have been used by a number of different laboratories, including structural magnetic resonance imaging and postmortem studies of neuroanatomy. Neurobiological and neuropsychological data from individuals across a wide age range are examined from a neurodevelopmental perspective. We discuss how these recent advances have led us to develop a growth dysregulation hypothesis of autism. Finally, we discuss how this hypothesis may lead to new innovations in autism research.

Publisher

Cambridge University Press (CUP)

Subject

Psychiatry and Mental health,Developmental and Educational Psychology

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