Length of the chromosomal segment marked by galactose-1-phosphate uridyl transferase and soluble aconitase and conserved since divergence of lineages leading to mouse and man

Abstract

SummaryStandard linkage testing crosses and ovarian teratoma mapping were used to estimate the length of the chromosomal segment that is marked by galactose-1-phosphate uridyl transferase and soluble aconitase and that has been conserved since divergence of lineages leading to mouse and man. These experiments were also used to determine whether theRb(4·6)2BnrRobertsonian translocation suppresses recombination on the proximal portion of mouse Chromosome 4. The estimated length of the conserved segment marked by galactose-1-phosphate uridyl transferase and soluble aconitase in mouse and man was estimated to be 24 cM. It was also shown thatRb(4·6)2Bnrstrongly suppressed recombination on the centromeric portion of mouse Chromosome 4.