Author:
Barthelmess Ilse B.,Kolanus Johanna
Abstract
SummarySeveral amino-acid synthetic enzymes, belonging to arginie, glutamine, leucine, lysine and phenylalanine biosynthesis, respectively, were investigated under conditions of reduced availability of any one of 16 out of the 20 amino acids represented in proteins. The enzymes showed simultaneous derepression under each condition, albeit to different degrees. Derepression was abolished and the remaining basal enzyme levels reduced by mutations at thecpc-1locus which governs general amino-acid control inNeurospora. Glutamine synthetase was shown to be undercpc-1and additional controls. The evidence emphasizes the global nature of general amino-acid control.
Subject
Genetics,General Medicine
Cited by
9 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献