Author:
De Benedictis Giovanna,Capalbo P.,Gallina E.
Abstract
SUMMARYAlloimmunization in sheep revealed an antigen specificity B1 which is also to be found in cattle sera. The molecular weight of the protein carrying B1 was greater in sheep than in cattle, whilst in both cases its isoelectric point was at pH 6·2. The electrophoretic position of the antigen suggests that the molecule carrying B1 might be a β-globulin. Family studies indicated that in both species B1 was inherited in a simple Mendelian manner, as if it were a product of a dominant alleleB1at an autosomal locusB.
Subject
Genetics,General Medicine
Reference15 articles.
1. Precipitin reactions between extracts of seeds of Canavalia ensiformis (jack bean) and normal and pathological serum proteins;Harris;Vox Sanguinis,1963
2. Immunochemistry of two polymorphic antigens identified in sheep serum (Ovis aries);De Benedictis;International Journal of Immunochemistry,1979
3. A serum antigen detected in cattle by micro-immuno-diffusion
4. Immunogenetics of a sheep (Ovis aries) serum antigen