Non-disjunction and maternal age inD. melanogaster

Author:

Kelsall P.

Abstract

The frequencies of non-disjunction at first and second meiotic division, in both male and female ofDrosophila melanogaster, are estimated. Numbers of exceptional individuals scored in several broods of increasing parental age are also presented. These results fail to show any evidence of an age-effect. Work claiming to demonstrate the existence of an age effect inDrosophilais reinvestigated. The importance of these results and their relevance to human studies are discussed.

Publisher

Hindawi Limited

Subject

Genetics,General Medicine

Reference12 articles.

1. Mechanisms of Meiotic Non-disjunction in Man

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3. The relative effects of paternal and maternal age in mongolism

4. A comparison of the percentages of non-disjunction in successive broods;Anderson;Pap. Mich. Acad. Sci.,1927

5. Parental age in achondroplasia and mongolism;Penrose;Amer. J. hum. Genet.,1957

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