Author:
Ibarra O.F.,Jenkings D.C.
Abstract
AbstractThe response of the free-living stages of Nippostrongylus brasiliensis, Nematospiroides dubius, Haemonchus contortus, Trichostrongylus colubriformis and Ostertagia ostertagi to a wide variety of antiparasitic agents in vitro was investigated.All the major broad spectrum veterinary anthelmintics showed good activity against each of these worms with EC30 values varying from about 00002mg/1 for certain benzimidazoles and ivermectin to about 6–5 mg/1 for febantel. Of 22 known narrow spectrum anthelmintics useful only against H. contortus and/or helminths other than trichostrongyles, only 10% showed good activity at concentrations equal to or less than 100mg/1. Further, only one of 15 antiprotozoal agents showed good activity in these tests at the 100mg/1 level.
Publisher
Cambridge University Press (CUP)
Subject
Animal Science and Zoology,General Medicine,Parasitology
Cited by
23 articles.
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