Abstract
AbstractThe life span and the pathogenicity of amphistomes developing from Cercariae indicae XXVI (Paramphistomum epiclitum) were considerably reduced when the metacercariae were gamma-irradiated at 2krad or 3krad. The higher irradiation dose resulted in the complete absence of the flukes in infected animals. Single vaccination of lambs and kids with 3000 metacercariae irradiated at 2 krad or 3 krad stimulated a significant degree of resistance against challenge with 5000 non-irradiated metacercariae. The resistance was more pronounced in the group vaccinated with metacercariae irradiated at 3krad.
Publisher
Cambridge University Press (CUP)
Subject
Animal Science and Zoology,General Medicine,Parasitology
Cited by
8 articles.
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