Leiomyosarcoma of Small Vein From Forearm

Abstract

Although some 120 cases of leiomyosarcomas of large arteries and veins have been reported since the original case cited by Perl in 1981, with an additional 30 cases of smooth muscle tumors from major veins reported in 1960, it is an unusual event to find malignant smooth muscle tumors arising from the walls of smaller vessels. This report concerns a rather rare type of leiomyosarcoma involving the veins of the upper extremity, having its origin in the antecubital vein in the forearm of a 65 year old white male. The tumor was 2 cm in diameter and pearly white, smooth and somewhat lobulated in configuration. The tumor cells are moderately enlarged and flattened occurring in groups. Cells are arranged in various patterns and whorls. Mitotic figures are frequently observed.