Author:
Hamel E.,Bedard D.,Laviolette F.,Butterworth R. F.,Barbeau A.
Abstract
SUMMARY:The combined metabolic stresses of fasting and the intravenous injection of 50 mg nicotinic acid in Friedreich's ataxia resulted in the delineation of two sub-groups of responses. High bilirubin ataxics maintained abnormally elevated levels of bilirubin, while normal bilirubin ataxics behaved like the normal control group. It is postulated that this finding infers the possible linkage of the gene for Friedreich's ataxia and that for Gilbert's disease.
Publisher
Cambridge University Press (CUP)
Subject
Neurology (clinical),Neurology,General Medicine
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1. Friedreich's ataxia: Electrophysiologic and histologic findings in patients and relatives;Muscle & Nerve;1987-07
2. Plasma Cholesteryl Sulfate in Friedreich's ataxia;Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques;1984-11
3. Reduced Formation of Hippuric Acid After Oral Benzoic Acid in Friedreich’s Ataxia;Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques;1982-05
4. Lipids and lipoproteins in Friedreich's ataxia.;Journal of Neurology, Neurosurgery & Psychiatry;1980-02-01
5. Erythrocyte Protoporphyrin Levels in Patients with Friedreich's and other Ataxias;Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques;1979-05